Table 4 of Zhu, Mol Vis 2010; 16:740-755. Table 4 of Zhu, Mol Vis 2010; 16:740-755.
Table 4. Clusters of genes differentially regulated between inferior and superior retina, with possible impact on photoreceptor vulnerability and survival.
| Symbol | Description | RefSeq | FR (inf) | FR (sup) | FM |
|---|---|---|---|---|---|
| Complement system (p=1.66E-07) | |||||
| C1qb | complement component 1, q subcomponent, beta polypeptide | NM_009777 | 4.20 | 1.45 | 2.75 |
| C1qc | complement component 1, q subcomponent, C chain | NM_007574 | 4.21 | 1.93 | 2.28 |
| C1qa | complement component 1, q subcomponent, alpha polypeptide | NM_007572 | 3.69 | 1.68 | 2.01 |
| C3ar1 | complement component 3a receptor 1 | NM_009779 | 1.96 | 1.02 | 0.95 |
| C3 | complement component 3 | NM_009778 | 2.23 | 1.28 | 0.94 |
| Acute phase response signaling, IL-10 signaling (p=1.8E-04–4.07E-03) | |||||
| Bcl3 | B-cell leukemia/lymphoma 3 | NM_033601 | 3.89 | 1.48 | 2.42 |
| Socs3 | suppressor of cytokine signaling 3 | NM_007707 | 2.12 | 1.13 | 1.00 |
| Stat3 | signal transducer and activator of transcription 3 | NM_213659 | 2.40 | 1.44 | 0.96 |
| Ophthalmic disorders (p=5.10E-04) | |||||
| Timp1 | tissue inhibitor of metalloproteinase 1 | NM_001044384 | 2.74 | 1.14 | 1.61 |
| Ccl3 | chemokine (C-C motif) ligand 3 | NM_011337 | 2.46 | 1.06 | 1.40 |
| C3ar1 | complement component 3a receptor 1 | NM_009779 | 1.96 | 1.02 | 0.95 |
| C3 | complement component 3 | NM_009778 | 2.23 | 1.28 | 0.94 |
| Slc16a12 | solute carrier family 16 (monocarboxylic acid transport) | NM_172838 | 0.77 | 1.33 | −0.56 |
| Vcan | versican | NM_001081249 | 0.91 | 1.48 | −0.57 |
| Nr2e3 | nuclear receptor subfamily 2, group E, member 3 | NM_013708 | 0.84 | 1.45 | −0.61 |
| Oxidative stress response (p=1.66E-04) | |||||
| Mt2, Mt1e | metallothionein 2 | NM_008630 | 2.41 | 1.39 | 1.02 |
| Mt1, Mt1f | metallothionein 1 | NM_013602 | 1.57 | 1.06 | 0.51 |