Figure 3. International-standard full-field electroretinogram of the two affected individuals of the optic atrophy family. This figure shows the electroretinogram (ERGs) from the right (row 1) and left (row 2) eye of patient IV:2, from the right (row 3) and left (row 4) eye of patient IV:1, and typical normal examples for comparison (row 5, bottom row). Dark-adapted ERGs are shown for flash intensities of 0.01 and 11.5 cd seconds per square meter (cd.s.m⁻²); light adapted ERGs are shown for 30 Hz flicker and 2 Hz stimulation at a flash intensity of 3.0 cd.s.m⁻². ON-OFF ERGs used an orange stimulus (560 cds per square meter [cd.m⁻²], duration 200 ms) superimposed on a green background (150 cd.m⁻²). S-cone ERGs used a blue stimulus (445 nm, 80 cd.m⁻²) on an orange background (620 nm, 560 cd.m⁻²). Broken lines replace blink artifacts occurring just after the b-wave peak in patient IV:1.