Figure 11. Pedigree diagram and haplotype analysis of the Algerian family with autosomal recessive optic atrophy and auditory neuropathy. The genotyping of microsatellite markers on chromosome 11q14.1–11q22.3 (localization of markers according to NCBI build 36.3) shows a common haplotype indicated by the black framed boxes in the two affected members (IV:1 and IV:2). Open squares represent unaffected males, open circles represent unaffected females, solid squares represent affected males, solid circles represent affected females, and the double line represent intermarriage.