Table 4 of Dimasi, Mol Vis 2010; 16:562-569.

Table 4. Association of haplotypes in PAX6 with CCT in the full cohort.

  SNP   p value
Haplotype 1 2 Frequency Additive Dominant Recessive
1 G C 0.63 0.008 0.369 0.003
2 G T 0.06 0.301 0.326 0.678
3 A C 0.31 0.025 0.009 0.579

A two SNP haplotype was constructed from PAX6 SNPs using rs3026398 (SNP 1) and rs662702 (SNP 2). This haplotype was assessed in 956 subjects from the full BMES cohort and tested for association with CCT as a continuous variable. Additive, dominant and recessive modes of inheritance were analyzed and values in bold survived Bonferroni correction for the three observed haplotypes. Values were considered significant at the p<0.05 level following correction.

Dimasi, Mol Vis 2010; 16:562-569. http://www.molvis.org/molvis/v16/a64

©2010 Molecular Vision http://www.molvis.org/molvis/

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