Figure 3. Electroretinograms of the patients affected with membrane-type frizzled-related protein, and related oculopathy. Electroretinograms (ERGs) and pattern ERGs of subject III-1 of family 4 (A), II-1 of family 1 (B), and III-3 of family 2 (C) show severely decreased rod photoreceptor function and moderately affected cone photoreceptor function. There is a moderate decrease in macular function, as shown by the pattern ERGs. Though similar ERG findings are seen in individual III-2 of family 2 (D), the pattern ERG is relatively well preserved, compared to normal case (E).