Figure 2. Autofluorescence images and high-resolution spectral domain optical coherence tomograms of affected patients with membrane-type frizzled-related protein, and related oculopathy. Autofluorescence images of the right (A) and left (B) eyes of posterior pole of individual III-1 of family 4 show relative preservation of the central macula. Optical coherence tomograms of the right (C) and left (D) fovea of individual II-1 of family 3 show areas of low reflectivity, which are due to cysts and relative thickening of the retina in the foveal region.