Figure 5 of Wang, Mol Vis 2010; 16:534-539.

Figure 5. Topology of AQP0 and mutation analysis. Four reported missense mutations are marked in black: R33C, E134G, T138R, R233K. The novel mutation, V107I, is marked in red. This mutation located at the extracellular loopC of AQP0. (Modified from [36], permission granted by Prof. Peter Agre).