Figure 3. Mutational analyses of Eph-receptor type-A2 in family PKCC118. A: Sequence chromatograms of wild type allele in individual 15 showing the translation of alanine. B: Individual 10, and C: individual 20 are heterozygous and homozygous for c.2353 G>A transition, respectively, which predicts the substitution of an alanine residue for a threonine residue at position 785 (Ala785Thr) in the Eph-receptor type-A2.