Table 6 of Asomugha, Mol Vis 2010; 16:476-494. Table 6 of Asomugha, Mol Vis 2010; 16:476-494.
Table 6. Compilation of PTMs found in crystallins and filaments in a 69-year-old human lens.
| Crystallins/filaments | Total post-translational modifications |
|---|---|
| αA | Acetylation: M1 |
| Ethylation: T13, H79, V89, I146 | |
| Methylation: H79, V89, Q90, I146, Q147, H154, R157 | |
| Oxidation: M1, W9, H154 | |
| αB | Acetylation: M1 |
| Carbamylation: M1, K92, E164 | |
| Deamidation: N146 | |
| Ethylation: H83, V93, Q108 | |
| Methylation: H83 | |
| Oxidation: M1, W9, W60, M68** | |
| βA3 | Carbamylation: K44, K131 |
| Deamidation: Q38, N40**, Q42**, N103, N133 | |
| Ethylation: W96, M126 | |
| Oxidation: W99, M126 | |
| Sulphone: M126 | |
| βA4 | Deamidation: N114 |
| Oxidation: M14 | |
| βB1 | Deamidation: N68*, N125, Q197, Q236* |
| Oxidation: W193 | |
| Phosphorylation: S81 | |
| βB2 | Acetylation: A2 |
| Deamidation: Q71, Q105, N114, N116, Q138, Q163, Q183 | |
| Ethylation: I109, K121, G161 | |
| Formylkynurenin***: W85, W151 | |
| Oxidation: W82, M122, H133, H135, W151 | |
| γD | Oxidation: M70, M147, W157 |
| γS | Carbamylation: I8** |
| Deamidation: Q17**, Q93**, Q171 | |
| Ethylation: I8, K14, K159 | |
| Formylkynurenin***: W163 | |
| Kynurenin***: W163** | |
| Methylation: H87, K159 | |
| Oxidation: W163 | |
| Phosphorylation: S167 | |
| CP49 | Oxidation: M175 |