Figure 3. Luciferase activities for
detection of protein–protein interactions involving various ΔG91
mutants. Luciferase activity values are expressed as fold activation
relative to the basal control (pCMV-AD+pCMV-BD). Various plasmid
constructs were co-transfected as labeled. Data represent the mean±SEM
of results in three independent experiments. Group differences were all
compared with wild type homodimer interaction (pAD-βA3+pBD-βA3). The
asterisk indicates a p<0.05 and the double asterisk indicates a
p<0.01.