Figure 1. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis of rs11771 and rs11266282 in LHON patients and normal controls. A: The C/T genotype of rs11771 in the DYNLT3 gene was analyzed using HindIII digestion. B: The T/A genotype of rs11266282 in the LANCL3 gene was analyzed using HinfI digestion. M: Size marker of 50 bp DNA ladder (from bottom to top: 50 bp, 100 bp, 150 bp, 200 bp, 250 bp, 300 bp, 350 bp, 400 bp, 450 bp, 500 bp, 600 bp, 700 bp, 800 bp, 900 bp, and 1000 bp).