Figure 1. Pyknotic cells in the retinal blood vessels and neuroretina. Histopathological examination was performed by light microscopy of hematoxylin and eosin-stained sections of porcine retina from the eye exposed to ischemia-reperfusion and the sham-operated fellow eye. A: Artery and vein from an eye exposed to ischemia-reperfusion and the corresponding sham-operated eye. Pyknotic cell nuclei can occasionally be observed in the ischemia-reperfusion eyes (arrows) but not in the sham-operated eyes. B: Pyknotic cell nuclei are observed throughout the retinal sections, including the outer nuclear layer (ONL), inner nuclear layer (INL), and ganglion cell layer (GCL) of the ischemia-reperfusion eyes (arrows) but not in the corresponding sham-operated eyes.