Figure 1. The third hypervariable region sequence of the human leukocyte antigen (HLA)-DRB1 first domain of the alleles identified in patients and controls. Residues 51–80 are represented. In addition to the alleles included in the figure, the following rare alleles were also observed in this study: HLA-DRB1*0305, HLA-DRB1*0407, HLA-DRB1*0804, HLA-DRB1*1106, HLA-DRB1*1111, HLA-DRB1*1415, HLA-DRB1*1506, HLA-DRB1*1507, HLA-DRB1*1509, HLA-DRB1*1514, and HLA-DRB1*1602. Amino acid sequences are shown using the one-letter code. The epitope S57–LLEQRRAA (67–74) is highlighted.