Figure 1. Morphological examination of rat lens regeneration. Photographs of a rat eye (A, D, G, J, M, P, S), lens tissue (B, E, H, K, N, Q, T), and histologic analysis (C, F, I, L, O, R, U; hematoxylin and eosin staining) after ECLE. Continuous circular capsulorhexis of the anterior capsule and clear posterior capsule in a rat eye immediately after ECLE (A, B, C). On day 3, PCO is noted (D, E, F). On day 7, the eye shows development of clinically evident PCO (G, H), and Seomerring’s ring forms (G, H, I). On day 14, elongated lens fibers on the posterior capsule become well differentiated lens fibers (J, K, L).One month after ECLE, the region of anterior capsulorhexis is opaque, and the capsular bag is full of regenerated semitransparent lens material (M, N, O). Two to three months after ECLE (P-U), the regenerated lens is almost similar in size to the intact. Note the relatively loose packing of the elongating fiber cells. Abbreviations: a, anterior capsule; b, bow regions; c, cornea; e, lens epithelium; f, lens fiber cells; i, iris; p, posterior capsule; r, retina.