Table 3 of Yasuma, Mol Vis 2010; 16:2923-2930.

Table 3. Regression analyses of hs-CRP levels.

Genotype    
372_815del443ins54 genotype p value † p value ‡
Wild-type logarithm of serum CRP= 0.0097x [Age]-3.7 0.063  
Heterozygote 0.025x [Age]-4.6 2.4×10−7 0.016
Homozygote 0.039 x [Age]-5.2 0.0041  
Total 0.022x [Age]-4.4 2.9×10−7  
Effect of risk haplotype
gene-dosage model estimated regression coefficients (age) p value
Dominant wild-type 0.0098 0.054
  heterozygote + homozygote 0.027  
Recessive wild-type + heterozygote 0.02 0.15
  homozygote 0.04  
Additive wild-type 0.0097 0.027
  heterozygote 0.025  
  homozygote 0.04  

†The regression coefficients for age were statistically significant in heterozygotes (p<0.001), homozygotes (p=0.004), and all genotypes combined (p<0.001). ‡The regression coefficients for age were significantly different among three genotypes (p=0.016)

Yasuma, Mol Vis 2010; 16:2923-2930. http://www.molvis.org/molvis/v16/a314

©2010 Molecular Vision http://www.molvis.org/molvis/

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