Figure 2 of Pandaranayaka, Mol Vis 2010; 16:2891-2902.


Figure 2. Space-filling model in four orientations for modified myocilin proteins. Full length myocilin, deletions due to presence of stop codon and deletions/modifications due to possible alternative splicing caused by the single nucleotide polymorphism shown in the model, as explained in Figure 1. Different regions in the model are colored as follows; NH2-terminal region (Orange), coiled coil region (Pink), hinge region (Cyan), COOH-terminal region (Yellow), regions predicted to be deleted (White) due to stop codon mutation or possible alternative splicing, regions predicted to be modified due to possible alternative splicing.