Figure 1. Retinal ganglion cell viability
of seven experiments under (A) glutamate-induced neurotoxicity, (B)
oxidative
stress, and (C) hypoxic stress, with increasing
concentrations of brimonidine. Brimonidine at a concentration of 1 μM
significantly increased retinal ganglion cell (RGC) viability in all
three stresses. Abbreviations: (-) represents control RGC cultures
without glutamate; (+) represents control RGC cultures with glutamate,
AO(+)represents medium with anti-oxidant; AO(-) represents medium
without anti-oxidant, * represents p<0.01. n=7. Error bar indicates
SD.