Figure 3. Cone shedding in Nrl−/−
mice shows rhythmic activity in both cyclic light and constant
darkness. Phagosome counts were made made every 3 h throughout both the
light and dark periods under light-dark (LD) conditions (A) and
through subjective light and dark periods under constant darkness (DD)
conditions (B). A burst in the number of cone phagosomes was
seen at ZT1 (LD) and at circadian time (CT1; total darkness),
significantly different from all other values (***p<0.001).
Phagosome numbers were lowest in late daytime.