Table 1 of Ryu, Mol Vis 2010; 16:2811-2821. Table 1 of Ryu, Mol Vis 2010; 16:2811-2821.
Table 1. Summary of age-related eye disease study (AREDS) subjects genotyped on the Human 1 Bead-Chip panel and the subjects used for replication.
| AREDS subjects | Replication subjects | |||
|---|---|---|---|---|
| Variable | Cases | Controls | Cases | Controls |
| Number of AREDS subjects genotyped | 395 | 198 | 444 | 300 |
| Early AMD (%) | 14 (3.5%) | - | 202 (45.5%) | - |
| Geographic atrophy (%) | 134 (34%) | - | 67 (15.1%) | - |
| Exudation (%) | 197 (49.9%) | - | 175 (39.4%) | - |
| Both (%) | 50 (12.6%) | - | - | - |
| Control (%) | - | 171 (86.4%) | - | 300 (100%) |
| Questionable control (%) | - | 27 (13.6%) | - | - |
| Mean age (SD) in years | 79.6 (4.98) | 77.6 (4.8) | 77.3 (9.3) | 69.6 (8.3) |
| Male: Female ratio | 0.73 | 1.04 | 0.56 | 0.88 |
| Smoking status | ||||
| % Never smoked | 41.5% | 49.5% | 44.1% | 50.3% |
| % Previously smoked | 47.9% | 44.4% | 46.0% | 41.7% |
| % Currently smoke | 10.6% | 6.1% | 5.4% | 5.0% |
| % Smoking Unknown | 0% | 0% | 4.5% | 3.0% |
| Race | ||||
| % White, non-Hispanic | 99.0% | 0.9495 | 98.9% | 99.3% |
| % White, Hispanic | 0% | 0 | 1.1% | 0.3% |
| % White, Unknown | 0% | 0 | 0% | 0.3% |
| % Black, non-Hispanic | 0. 5% | 5.0% | 0% | 0% |
| % Other | 0.5% | 0% | 0% | 0% |