Table 5 of Abu-Amero, Mol Vis 2010; 16:2805-2810.

Table 5. Summary of the genetics association of the two coding SNPs in the LOXL1 gene as reported in various populations.

  rs1048661
 “G” Allele rs3825942
 “G” allele  
Studied population Case Control Significant association Case Control Significant association Reference
American 0.819 0.600 0.000036 0.986 0.880 0.0003 [8]
American 0.787 0.665 0.0222 0.939 0.844 0.0194 [24]
American 0.843 0.703 7.74×10−19 0.959 0.798 3.10×10−17 [25]
American 0.829 0.719 0.0031 0.988 0.795 1.3×10−13 [26]
Australian 0.780 0.660 8.49×10−4 0.950 0.840 7.83×10−5 [9]
Austrian 0.841 0.671 <0.001 0.994 0.817 <0.001 [10]
Chinese 0.542 0.444 0.142 0.992 0.918 0.0018 [15]
Finnish 0.825 0.683 2.65×10−5 0.968 0.823 2.24×10−8 [27]
Germany 0.818 0.644 3.16×10−8 0.951 0.857 6.5×10−13 [11]
Iceland 0.781 0.651 1.8×10−6 0.984 0.847 4.1×10−9 [6]
Indian 0.721 0.634 0.156 0.923 0.742 0.0001 [14]
Italian 0.825 0.693 2.90×10−19 1.000 0.821 1.28×10−40 [12]
Japanese 0.005 0.554 >0.05 0.993 0.806 1.7×10−8 [19]
South African 0.990 0.810 1.7×10−5 0.130 0.620 5.2×10-13• [23]
Swedish 0.834 0.682 2.7×10−7 0.995 0.879 9.1×10−14 [6]
Saudi Arabian 0.876 0.762 0.0056 0.968 0.817 0.000005 This study

•The p value reported here is in favor of the controls as the G allele was more frequent in controls (0.620) than in patients (0.130). In the South African population, the opposite allele “A” was the risk allele [23].

Abu-Amero, Mol Vis 2010; 16:2805-2810. http://www.molvis.org/molvis/v16/a300

©2010 Molecular Vision http://www.molvis.org/molvis/

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