Table 1 of Ayub, Mol Vis 2010; 16:18-25. Table 1 of Ayub, Mol Vis 2010; 16:18-25.
Table 1. Genotype and allele frequencies of intron 4 polymorphism of eNOS in controls and patients.
Genotype |
Controls (n=166) |
POAG (n=159) |
p (χ2) | p (χ2) | Odds ratio (95% CI) |
PCAG (n=111) |
p (χ2) | p (χ2) | Odds ratio (95% CI) |
|---|---|---|---|---|---|---|---|---|---|
| b/b | 139 (83.7%) | 111 (70%) | <0.05 (8.89) | <0.01 (8.87) | DM=2.23 (1.26–3.39) p<0.01 | 79 (71%) | <0.05 (6.33) | 0.01 (6.26) | DM=2.09 (1.12–3.89) p<0.01 |
| b/a | 21 (12.7%) | 38 (24%) | <0.01 (6.92) | 24 (22%) | <0.05 (3.93) | ||||
| a/a | 6 (3.6%) | 10 (6%) | >0.05 (1.24) | RM=1.79 (0.58–5.69) p>0.05 | 8 (7%) | >0.05 (1.79) | RM=1.16 (0.40–3.31) p>0.05 | ||
| Allele | Controls | POAG | p (χ2) | Odds ratio (95% CI) | PCAG | p (χ2) | Odds ratio (95% CI) | ||
| b | 299 (90%) | 260 (82%) | <0.01 (9.29) | 2.02 (1.25–3.28) p=0.001 | 182 (82%) | <0.01 (7.59) | 1.99 (1.18–3.37) p<0.01 | ||
| a | 33 (10%) | 58 (18%) | 40 (18%) |