Figure 1. Pedigree of a Danish family with a North Carolina macular dystrophy-like phenotype. Individuals found to be clinically affected with North Carolina macular dystrophy (NCMD) are represented by black symbols, while unaffected individuals are depicted with open symbols. Family members with unknown affection status and family members that did not meet full criteria for a clinical diagnosis of NCMD are indicated with gray symbols. Individuals that are deceased are marked with a slash. Genotypes from seven genetic markers on the long arm of chromosome 5 are shown with the most telomeric markers at the top. The genotypes detected for each marker are shown beneath each subject’s pedigree symbol to the right of the marker name. The linked allele of each marker is on the left and boxed. If analysis of the genotypes revealed a meiotic recombination, the box around the recombinant allele is shaded black; if no recombination was detected, the box has been left unshaded. If the presence of a recombination could not be determined, the box is shaded gray. Genotypes that could not be determined are indicated with a dash, while those genotypes that were inferred are indicated with an asterisk. The positions of the markers on chromosome 5 are shown based on the GRCh37/hg19 build of the human genome.