Figure 2. Zn2+ or
oxidative-stress-induced death was attenuated by Zn2+
therapeutics. A: Pyruvate, nicotinamide, NAD+, TPEN,
and sirtinol variably attenuated ethacrynic acid, H2O2,
zinc toxicity in the 661 W cone photoreceptor cell line. B:
The effect of these exposures on Müller glial cells is presented. C:
effect of these exposures in ARPE-19 cells is presented (n=10–15).
* indicates difference from toxic exposure alone at p<0.05 by
one-way ANOVA and a Bonferroni test.