Figure 3. The effects of IKKβ-siRNA, MMC,
and PBS on bleb survival, bleb height, and bleb area. A:
IKKβ-siRNA (n=6) and MMC (n=4) groups significantly prolonged bleb
survival compared with the PBS group (n=4) in the monkey model (log
rank test; p<0.01), as shown in the Kaplan-Meier survival curve. B:
Higher
blebs
were
observed in the siRNA group than in the PBS group
(p<0.01), while the MMC group showed the highest blebs among the
three groups (p<0.01). C: Eyes in the siRNA and MMC groups
had significantly larger bleb area compared with the PBS group
(p<0.01), but there was no significant difference between the siRNA
and MMC groups (p=0.214).