Figure 1. Histology of the mouse eye after induction of chemical burns by 0.1 M NaOH. Chemical burns induced with 0.1 M NaOH induced severe inflammatory changes on the ocular surface. Representative figures are shown. A: Control eye, no chemical burn induced. B: Two days after chemical burn. Severe infiltration by inflammatory cells and total loss of the epithelial layer are observed. C: Seven days after chemical burn. Corneal inflammation is reduced compared to day 2; corneal edema persists; epithelial layer has regenerated. D: Thirty days after chemical burn. Inflammation has almost completely subsided; however, marked increases in corneal stromal thickness and cellularity persist.