Figure 4. The protein levels of occludin
and intercellular adhesion molecule-1 in paired control retinae
significantly decreased and increased, respectively, over time. A:
Western
blots had been used to assess occludin and intercellular
adhesion molecule-1 (ICAM-1) protein levels in retinae. B: The
expression of occludin in treated eyes increased significantly at
months 3 and 6 compared with paired control eyes. C: The
expression of ICAM-1 in treated eyes was obviously lower than that in
the paired control eyes (p<0.01) but still higher than that in
normal control eyes (p<0.01). *Values of treatment were compared to
that of normal control, p value <0.05. #Values of treatment were
compared to that of paired control, p value <0.01. Abbreviations:
DM1 represents diabetes 1 month, DM3 represents diabetes 3 months, DM6
represents diabetes 6 months, CON represents normal control group, CONf
represents sham-injected normal control group, t represents treatment.