Table 2 of Richardson, Mol Vis 2010; 16:2376-2383. Table 2 of Richardson, Mol Vis 2010; 16:2376-2383.
Table 2. Proteins with altered levels identified with LC-MS/MS in the albumin-depleted fraction of AH of patients with FECD.
Protein ID |
Protein common name |
Protein coverage (%) |
Number of unique sequences |
CV (%) Fuchs |
CV (%) normal |
Fold change in FED patients |
p value |
|---|---|---|---|---|---|---|---|
| IPI00790473 | 12 kDa protein | 12.3 | 1 | 132.4 | 65.4 | 1.6 | 0.37 |
| IPI00789547 | 19 kDa protein | 10.3 | 1 | 113.2 | 62.3 | −1.2 | 0.58 |
| IPI00940791 | 20 kDa protein | 42.2 | 7 | 99.8 | 54.7 | −1.4 | 0.35 |
| IPI00793626 | 22 kDa protein | 11.2 | 1 | 155.0 | 91.6 | 2.0 | 0.31 |
| IPI00942787 | 42 kDa protein | 27.5 | 12 | 138.0 | 78.7 | 1.1 | 0.80 |
| IPI00019943 | Afamin | 6.7 | 2 | 66.0 | 48.1 | −2.2 | 0.004 |
| IPI00022429 | Alpha-1-acid glycoprotein 1 | 41.3 | 10 | 113.8 | 90.8 | −1.4 | 0.45 |
| IPI00020091 | Alpha-1-acid glycoprotein 2 | 39.8 | 8 | 115.0 | 82.2 | −1.4 | 0.46 |
| IPI00847635 | Alpha-1-antichymotrypsin | 23.9 | 8 | 119.8 | 77.9 | 1.1 | 0.76 |
| IPI00553177 | Alpha-1-antitrypsin | 56.7 | 22 | 135.2 | 81.1 | 1.1 | 0.91 |
| IPI00022895 | Alpha-1B-glycoprotein | 30.1 | 10 | 116.5 | 56.3 | 1.2 | 0.68 |
| IPI00166729 | alpha-2-glycoprotein 1, zinc precursor | 33.2 | 7 | 100.3 | 68.5 | −1.1 | 0.85 |
| IPI00922262 | Alpha-2-HS-glycoprotein | 11.8 | 1 | 120.2 | 201.3 | −6.5 | 0.19 |
| IPI00478003 | Alpha-2-macroglobulin | 17.2 | 16 | 92.0 | 57.3 | −1.5 | 0.21 |
| IPI00032220 | Angiotensinogen | 19.0 | 6 | 93.1 | 61.3 | −1.2 | 0.57 |
| IPI00032179 | Antithrombin-III | 28.7 | 10 | 79.3 | 44.2 | −1.5 | 0.15 |
| IPI00021841 | Apolipoprotein A-I | 39.7 | 10 | 103.8 | 65.0 | 1.2 | 0.71 |
| IPI00021854 | Apolipoprotein A-II | 51.0 | 4 | 164.2 | 107.6 | 1.2 | 0.73 |
| IPI00304273 | Apolipoprotein A-IV | 6.8 | 2 | 96.2 | 107.0 | −1.1 | 0.81 |
| IPI00298828 | Beta-2-glycoprotein 1 | 9.3 | 2 | 63.0 | 54.9 | −1.8 | 0.03 |
| IPI00004656 | Beta-2-microglobulin | 18.5 | 1 | 95.9 | 121.0 | −2.3 | 0.16 |
| IPI00910009 | cDNA FLJ53554 | 6.6 | 1 | 66.0 | 22.5 | −1.1 | 0.63 |
| IPI00384508 | cDNA FLJ61725 | 0.7 | 1 | 84.5 | 91.8 | −1.3 | 0.53 |
| IPI00017601 | Ceruloplasmin | 35.2 | 23 | 80.4 | 50.4 | −1.2 | 0.47 |
| IPI00002147 | Chitinase-3-like protein 1 | 3.9 | 1 | 126.3 | 74.0 | 1.2 | 0.73 |
| IPI00291262 | Clusterin | 12.3 | 4 | 83.7 | 47.4 | −1.2 | 0.48 |
| IPI00942927 | Complement C3 | 3.9 | 2 | 125.9 | 33.4 | −2.6 | 0.002 |
| IPI00843913 | Complement component 4A | 7.4 | 7 | 109.0 | 73.6 | 1.1 | 0.77 |
| IPI00887154 | Complement component 4B | 7.4 | 7 | 109.0 | 73.6 | 1.1 | 0.77 |
| IPI00032293 | Cystatin-C | 19.2 | 3 | 114.2 | 54.0 | −1.2 | 0.63 |
| IPI00940990 | Dickkopf-related protein 3 | 21.7 | 5 | 92.9 | 82.6 | −1.1 | 0.78 |
| IPI00156171 | Ectonucleotide pyrophosphatase/ phosphodiesterase family member 2 | 2.6 | 1 | 89.7 | 82.6 | −1.6 | 0.20 |
| IPI00026199 | Glutathione peroxidase 3 | 25.7 | 5 | 68.8 | 47.3 | −1.1 | 0.64 |
| IPI00641737 | Haptoglobin | 25.0 | 12 | 138.0 | 78.7 | 1.1 | 0.80 |
| IPI00477597 | Haptoglobin-related protein | 14.4 | 5 | 129.2 | 98.3 | 1.1 | 0.90 |
| IPI00022488 | Hemopexin | 56.3 | 18 | 128.9 | 82.0 | 1.0 | 0.95 |
| IPI00022371 | Histidine-rich glycoprotein | 9.7 | 3 | 65.2 | 43.2 | −2.2 | 0.002 |
| IPI00431645 | HP protein | 15.3 | 3 | 139.5 | 73.5 | 1.3 | 0.60 |
| IPI00785084 | IGH@ protein | 27.5 | 8 | 83.9 | 45.8 | −2.0 | 0.01 |
| IPI00784985 | IGK@ protein | 30.2 | 4 | 127.7 | 37.4 | 1.3 | 0.55 |
| IPI00784935 | IGL@ protein | 12.8 | 2 | 84.0 | 99.0 | −2.2 | 0.12 |
| IPI00292150 | Latent-transforming growth factor beta-binding protein 2 | 1.0 | 1 | 81.5 | 166.4 | 1.6 | 0.32 |
| IPI00022417 | Leucine-rich alpha-2-glycoprotein | 9.8 | 2 | 132.3 | 84.1 | −1.2 | 0.69 |
| IPI00021000 | Osteopontin | 10.2 | 2 | 118.4 | 91.2 | 1.5 | 0.39 |
| IPI00006114 | Pigment epithelium-derived factor | 45.2 | 14 | 108.2 | 71.2 | 1.2 | 0.59 |
| IPI00291866 | Plasma protease C1 inhibitor | 7.4 | 3 | 118.9 | 84.0 | 1.5 | 0.37 |
| IPI00514285 | Prostaglandin D2 synthase 21 kDa | 14.7 | 2 | 93.9 | 62.8 | 1.1 | 0.73 |
| IPI00013179 | Prostaglandin-H2 D-isomerase | 36.3 | 4 | 91.1 | 60.9 | 1.0 | 0.93 |
| IPI00334282 | Protein FAM3C | 7.1 | 1 | 61.1 | 34.7 | −1.8 | 0.004 |
| IPI00556287 | Putative uncharacterized protein | 18.0 | 2 | 120.7 | 33.8 | 1.0 | 0.98 |
| IPI00514530 | Putative uncharacterized protein ACTA1 | 8.3 | 2 | 131.0 | 82.5 | −1.5 | 0.40 |
| IPI00022434 | Putative uncharacterized protein ALB | 37.3 | 19 | 91.7 | 70.2 | 1.2 | 0.56 |
| IPI00924948 | Putative uncharacterized protein AZGP1 | 31.7 | 5 | 104.6 | 66.6 | −1.2 | 0.66 |
| IPI00930072 | Putative uncharacterized protein DKFZp686E23209 | 9.8 | 4 | 77.4 | 63.7 | 1.1 | 0.71 |
| IPI00930442 | Putative uncharacterized protein DKFZp686M24218 | 13.7 | 4 | 79.0 | 83.8 | −1.8 | 0.15 |
| IPI00022337 | Retinol-binding protein 3 | 1.9 | 1 | 205.7 | 165.7 | 1.0 | 1.00 |
| IPI00014048 | RNase pancreatic | 28.9 | 2 | 128.6 | 95.5 | −1.0 | 0.97 |
| IPI00386812 | RIG-like 7–1 | 23.4 | 2 | 121.1 | 39.8 | 1.9 | 0.21 |
| IPI00022463 | Serotransferrin | 64.5 | 59 | 103.1 | 59.1 | 1.0 | 0.93 |
| IPI00745872 | Serum albumin | 57.5 | 32 | 78.0 | 57.0 | 1.0 | 0.90 |
| IPI00383164 | SNC66 protein | 19.1 | 6 | 96.2 | 61.5 | −1.2 | 0.65 |
| IPI00373937 | Suprabasin | 7.3 | 1 | 80.8 | 96.2 | 3.7 | 0.01 |
| IPI00022432 | Transthyretin | 69.4 | 11 | 103.8 | 55.5 | −1.1 | 0.72 |
| IPI00555812 | Vitamin D-binding protein | 35.4 | 11 | 116.0 | 30.6 | 1.3 | 0.55 |