Table 5 of Böhringer, Mol Vis 2010; 16:2362-2367.

Table 5. Validation of the thresholds for HLA-class I histocompatibility and the tolerance induction from Table 4.

Factor Hazards ratio p-value
Tolerogenic factor higher than 220 eplets2 2.00 <0.01
More than 10 HLAMatchmaker eplets at HLA-A/-B 1.50 0.02
Risk estimation at time of keratoplasty (low versus high risk) 0.56 <0.01

This Cox model is fitted to cohort 2 comprising of 975 consecutive patients. The model is adjusted for low- versus high-risk keratoplasties. Immune reactions were the only endpoint.

Böhringer, Mol Vis 2010; 16:2362-2367. http://www.molvis.org/molvis/v16/a253

©2010 Molecular Vision http://www.molvis.org/molvis/

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