Figure 1. Kaplan–Meier estimations of rejection free survival for the 975 patients in cohort 2. The HLA-class I matched (less or equal 10 mismatched HLAMatchmaker eplets) and non-matched (>10 mismatched HLAMatchmaker eplets) sub-groups are displayed separately. More immune reactions occur when tolerance factor higher than 220 eplets² (light gray) in comparison to keratoplasties with the tolerance factor lower or equal than 220 eplets² (dark gray). This difference seems to be even more pronounced in the non-HLA-class I matched subgroup.