Table 2 of Zeng, Mol Vis 2010; 16:2273-2278.

Table 2. Association between complement factor D (CFD) single nucleotide polymorphism (SNP) rs1651896 and advanced age related macular degeneration (AMD) in the discovery, replication and combination cohorts

Cohort Phenotype N MAF (A) HWE p (allelic)
Discovery Advanced AMD 178 0.374 4.21E-01 0.07
Cohort Control 161 0.307 9.97E-01  
Replication Advanced AMD 445 0.372 9.52E-01 0.882
Cohort Control 190 0.376 8.41E-01  
Combination Advanced AMD 623 0.372 9.05E-01 0.223
Cohort Control 351 0.345 9.21E-01  
HapMap-CEU Control 112 0.321    

Shown are the corresponding numbers of the CFD SNP rs1651896 for both advanced AMD and control groups in the discovery cohort, replication cohort, and combination cohort. Frequencies for the minor allele in our cohorts and HapMap European group, hardy Weinberg equation (HWE) test, and P(allelic) values are given.

Zeng, Mol Vis 2010; 16:2273-2278. http://www.molvis.org/molvis/v16/a243

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