Figure 2. LOXL1 gene expression in drug-treated (1:1,000 and 1:100) hLEC using real-time PCR. Data were normalized to β-actin (ACTB). Values represent percent of normal expression in controls ±SEM of three separate experiments. No significant decrease in expression was observed in any of the samples. Significant increases in expression were seen in the Brinzolamide 1:100, Timolol 1:100, and Latanoprost 1:100 groups. * denotes a p-value <0.003, ** denotes a p-value <0.03, and *** denotes a p-value <0.05.