Molecular Vision: Zhou, Mol Vis 2010; 16:2163-2174. Table 3

Table 3. Protein expression in posterior sclera: MD eyes versus normal control eyes (NC).

Spot no.^a	Protein level	Fold	Accession number^b	Protein description	Protein score^c
3	Up	3.2	gi\|61365690	adenylate kinase 1	119
42	Up	8.8	gi\|73995384	beta A4-crystallin	101
181	Up	3.5	gi\|78195022	Fe-S type hydro-lyases tartrate/fumarate alpha region	66
232	Up	10.5	gi\|68417708	Ca²⁺-dependent activator protein for secretion 2 isoform b, partial	41
36	Up	N/MD^d	gi\|61822969	junctophilin 1, partial	42
45	Up	N/MD	gi\|13936373	glutathione S-transferase subunit gYc	132
22	Down	3.5	gi\|4557920	G12v mutant of human placental Cdc42 GTPase in the GDP form chain B	123
67	Down	3.6	gi\|12407849	peroxiredoxin 4	94
89	Down	3.4	gi\|32400726	putative alpha-tubulin	97
143	Down	3.6	gi\|60813640	eukaryotic translation initiation factor 3 subunit 2 beta	82
159	Down	3.0	gi\|73980918	macrophage capping protein (Actin-regulatory protein CAP-G)	103
206	Down	3.3	gi\|25777724	aldehyde dehydrogenase 1A2 isoform 1	91
208	Down	3.2	gi\|76618159	tubulin alpha-2 chain	126
235	Down	3.3	gi\|78167676	ATPase	52
24	Down	^eD/NC^m	gi\|1001946	adenine phosphoribosyltransferase	95
41	Down	D/NC^m	gi\|55824562	peroxiredoxin 1	179
44	Down	D/NC^m	gi\|6978713	beta B2-crystallin	148
99	Down	D/NC^m	gi\|52138659	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	221

^aSpot no. is the unique sample spot protein number assigned by the PDQuest software. ^bAccession number is the MASCOT result of MALDI-TOF searched from the NCBInr database. ^cProtein score was from MALDI-TOF identification. The proteins that had a statistically significant protein score of great than 76 (p<0.05) were considered successfully identified. ^dN/MD, the protein spots were newly induced in posterior sclera of the MD eyes. ^eD/NC^m, the protein spots were only detected in posterior sclera of the normal control eyes.