Figure 1. Photographs of individual II:4 in pedigree XT. Photos are taken in primary gaze (E) and in the 8 cardinal gaze positions (A, B, C, D, F, G, H, and I). This subject demonstrates marked ophthalmoparesis, infraducted eyes in primary position, exotropia, and an inability to raise the eyes above midline. This patient also has bilateral ptosis (not shown).