Figure 2. Effects of peptides on the migration of RF/6A cells stimulated by vascular endothelial growth factor. Bevacizumab and peptides
were added in the upper chamber containing RF/6A cells 30 min before the stimulation of vascular endothelial growth factor
(VEGF) in the lower chamber (100 ng/ml). After 24 h of incubation, migratory activity of the cells was estimated. Bevacizumab
and H-RN inhibited migration of RF/6A cells. H-FT and scrambled peptide did not inhibit migration up to 1 µM concentration,
whereas at 10 µM there was a mild inhibition (*p<0.05; **p<0.01, each condition versus control).