Molecular Vision: Tong, Mol Vis 2010; 16:1958-1981. Table 3

Table 3. The association between the HTRA1 gene polymorphisms and AMD—- Allele and genotype frequencies of case-control studies included in a meta-analysis

Ref	Year	Genotype distribution										AA / GG		AG / GG		A / G
		cases					controls					AA / GG		AG / GG		A / G
		N	AA	AG	GG	P value for HWE	N	AA	AG	GG	P value for HWE	OR1	95% CI	OR2	95% CI	OR	95% CI
[101]	2006	96	44	40	18	0.266	130	14	59	57	0.976	9.952	4.465~22.184	2.147	1.104~4.174	3.626	2.450~5.368
[98]	2007	242	67	108	67	0.247	157	8	50	99	0.877	12.375	5.583~27.432	3.192	2.022~5.039	3.723	2.693~5.158
[102]	2007	164	68	77	19	0.924	106	15	63	28	0.104	6.681	2.980~14.979	1.801	0.921~3.523	2.37	1.664~3.375
[105]	2007	123	45	55	26	0.488	133	22	57	54	0.582	4.248	2.127~8.487	2.004	1.103~3.640	2.231	1.566~3.178
[106]	2007	73	29	39	5	0.239	94	16	40	38	0.627	13.775	4.520~41.984	7.41	2.642~20.786	3.189	2.029~5.013
[95]	2007	457	102	183	172	<0.001	280	11	90	179	0.997	9.65	5.006~18.601	2.112	1.525~2.937	2.937	2.299~3.753
[99]	2007	118	32	57	29	0.937	116	5	41	70	0.948	15.448	5.476~43.582	3.356	1.860~6.055	3.734	2.498~5.583
[96]*	2007	134	43	54	37	0.0837	134	21	43	70	0.0111	3.874	2.009~7.469	2.376	1.350~4.180	2.358	1.657~3.347
[100]	2007	401	106	172	123	0.019	266	6	91	169	0.296	24.274	10.327~57.057	2.597	1.841~3.664	3.826	2.963~4.942
[97]*	2008	776	131	400	245	0.327	294	10	128	156	0.0282	8.341	4.253~16.360	1.99	1.500~2.640	2.042	1.652~2.525
[103]	2008	95	53	33	9	0.53	90	19	47	24	0.903	7.439	2.940~18.819	1.872	0.772~4.541	3.046	1.973~4.703
[104]	2008	163	94	51	18	0.0379	183	38	90	55	0.994	7.559	3.398~14.509	1.732	0.919~3.262	3.31	2.403~4.559
[108]	2008	229	90	89	50	0.0111	184	21	85	78	0.956	6.686	3.695~12.098	1.633	1.028~2.595	2.701	2.033~3.589
Total		3071					2167