Table 1 of Chen, Mol Vis 2010; 16:167-177. Table 1 of Chen, Mol Vis 2010; 16:167-177.
Table 1. Characters of reported cohorts of pseudoexfoliation syndrome/exfoliation glaucoma association with LOXL1 SNPs
First author |
Cohorts |
Sample size | Age (years) | Sex (Male %) | rs1048661 G% | rs2165241 T% | rs3825942 G% | Ref | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case | Control | Case | Control | Case | Control | Case | Control | Case | Control | Case | Control | |||
| Aragon-Martin | American | 287 | 333 | NA | NA | NA | NA | 84.3 | 70.3 | 73.4 | 44.8 | 95.9 | 79.8 | [12] |
| Challa* | American | 50 | 235 | 74.0±8.0 | 64.9±11.6 | 78.0 | 61.7 | 78.7 | 66.5 | 66.7 | 48.7 | 93.9 | 84.4 | [13] |
| Fan | American | 206 | 88 | 75 | 72 | NA | 43 | 82.9 | 71.9 | 76.0 | 45.6 | 98.8 | 79.5 | [14] |
| Fingert | American | 72 | 75 | NA | NA | NA | NA | 81.9 | 60.0 | NA | NA | 98.6 | 88.0 | [15] |
| Yang | American | 62 | 170 | NA | 74.2±8.8 | 38.7 | 52.9 | NA | NA | 83 | 53 | 100 | 85 | [16] |
| Hewitt* | Australian | 86 | 2087 | 76.4±8.1 | 68.6±10.0 | 37.2 | 44.8 | 78 | 66 | NA | NA | 95 | 84 | [17] |
| Mossbock | Austrian | 167 | 170 | 75.7 | 77.1 | 45.5 | 44.1 | 84.1 | 67.1 | NA | NA | 99.4 | 81.7 | [18] |
| Wolf | Germany | 128 | 280 | 71.9±9.7 | 66±13 | 44 | 41 | 84.4 | 66.0 | 78.2 | 49.1 | 99.2 | 85.6 | [19] |
| Pasutto | Germany | 517 | 348 | 76.6±8.5 | 73.9±6.4 | 44.5 | 43.4 | 81.8 | 64.4 | 75.2 | 48.2 | 95.1 | 85.7 | [20] |
| Pasutto | Italian | 209 | 70 | 78.3±7.7 | 75.2±7.4 | 39.2 | 35.7 | 82.5 | 69.3 | 79.8 | 51.5 | 100 | 82.1 | [20] |
| Thorleifsson | Icelandian | 130 | 14474 | NA | NA | NA | NA | 78.1 | 65.1 | 74.6 | 47.3 | 98.4 | 84.7 | [11] |
| Thorleifsson | Swedish | 199 | 198 | NA | NA | NA | NA | 83.4 | 68.2 | 81.3 | 53.5 | 99.5 | 87.9 | [11] |
| Lemmela | Finnish | 141 | 404 | NA | NA | NA | NA | 82.5 | 68.3 | 73.2 | 46.8 | 96.8 | 82.3 | [21] |
| Ramprasad | Indian | 52 | 97 | 68.9±11.4 | 64.1±7.2 | 51.9 | 53.6 | 72.1 | 63.4 | NA | NA | 92.3 | 74.2 | [28] |
| Lee | Chinese | 62 | 171 | 74.7±7.7 | 67.4±5.6 | 48.4 | 46.8 | 54.2 | 44.4 | NA | NA | 99.2 | 91.8 | [29] |
| Chen | Chinese | 50 | 124 | 70.4±7.6 | 63.8±5.1 | 62.0 | 57.6 | 11.0 | 48.0 | 2.0 | 10.0 | 100 | 90.0 | [30] |
| Fuse | Japanese | 56 | 138 | 74.8±6.2 | 68.0±7.7 | 55.4 | 55.1 | 3.6 | 49.3 | 1.8 | 5.8 | 100 | 87.7 | [22] |
| Hayashi | Japanese | 59 | 190 | 78.4±6.9 | 31.4±1.5 | 37.3 | 50.0 | 0.8 | 46.0 | NA | NA | 100 | 85.7 | [23] |
| Mabuchi | Japanese | 89 | 191 | 76.5±6.6 | 65.7±11.4 | NA | NA | 0.6 | 45.0 | NA | NA | 99.4 | 85.3 | [24] |
| Mori | Japanese | 95 | 190 | 75.7±8.1 | 65.0±6.8 | NA | NA | 0.5 | 47.4 | NA | NA | 99.5 | 85.0 | [25] |
| Ozaki | Japanese | 209 | 172 | 78.0±6.1 | 73.8±7.9 | 32.1 | 27.9 | 5.3 | 49.7 | 1.7 | 10.2 | 98.6 | 86.3 | [26] |
| Tanito | Japanese | 142 | 157 | 78.5±8.2 | 77.2±5.0 | 38.0 | 28.7 | 4.9 | 55.4 | 0.7 | 12.4 | 99.3 | 80.6 | [27] |