Figure 8. Meta-analysis of the association of single nucleotide polymorphism (SNP) rs3825942 with a combined group of exfoliation syndrome (XFS) and exfoliation glaucoma (XFG) in additive models. Squares indicate study-specific odds ratio (OR); the size of the box is proportional to the weight of the study; horizontal lines indicate 95% confidence interval (CI); diamond indicates summary OR with its corresponding 95% CI. Meta-analysis indicated that the heterozygote genotype (GA) does have higher susceptibility to XFS/XFG compared to AA genotype. C: Synthesized OR of SNP rs3825942 was 7.05 for XFS/XFG with dominant model (GG+GA versus AA).