Figure 2. Effects of SB-505124 on cell density. Rabbit subconjunctival fibroblasts were incubated with 10 µM of SB-505124 or 0.04% MMC
and then with or without TGF-β2 (2 ng/ml) in 12-well plates for 48 h (n=3).The number of cells was counted using a hemocytometer
after trypsinization. A reduction in cell number or cell loss was not observed with or without TGF-β2 in the SB-505124, but
was seen in the MMC treatment group . Asterisks indicate significant difference (p<0.05, Bonferroni multiple comparison).