Figure 4. Effect of bevacizumab on retinal
ganglion cell (RGC)-5 viability. Vascular endothelial growth factor
(VEGF) protected against hydrogen peroxide-mediated oxidative stress
compared with untreated controls, *p-value <0.005. This effect was
eliminated by using bevacizumab at the 2 mg/ml dose, p-value <0.001.
Cell numbers were determined using the Water Soluble Tetrazolium
(WST)-1 assay and are expressed as percent of control. H2O2:
peroxide, Bev: bevacizumab. Error bars are SEM n=8 for all