Figure 4. Effect of bevacizumab on retinal ganglion cell (RGC)-5 viability. Vascular endothelial growth factor (VEGF) protected against hydrogen peroxide-mediated oxidative stress compared with untreated controls, *p-value <0.005. This effect was eliminated by using bevacizumab at the 2 mg/ml dose, p-value <0.001. Cell numbers were determined using the Water Soluble Tetrazolium (WST)-1 assay and are expressed as percent of control. H₂O₂: hydrogen peroxide, Bev: bevacizumab. Error bars are SEM n=8 for all experiments.