Table 2 of Natoli, Mol Vis 2010; 16:1801-1822.

Table 2. Genes and ncRNA significantly regulated by treatment with photobiomodulation and saffron.

Probeset
ID
Gene assignment		 Gene
symbol
RefSeq
p-value		 FC
(LD/C)
10901166 angiopoietin-like 4 Angptl4 NM_199115 0.046613 2.20489
10738477 ADP-ribosylation factor 4-like Arf4l NM_001107052 0.027718 −2.12332
10865442 complement component 1, s subcomponent C1s NM_138900 0.027086 2.0311
10847761 Cd44 molecule Cd44 NM_012924 0.017188 2.40207
10771649 chemokine (C-X-C motif) ligand 11 Cxcl11 NM_182952 0.041843 2.71709
10827231 cysteine-rich, angiogenic inducer, 61 Cyr61 NM_031327 0.024324 2.07091
10890654 estrogen receptor 2 (ER beta) Esr2 NM_012754 0.009894 2.32768
10714890 Fas (TNF receptor superfamily, member 6) Fas NM_139194 0.01695 2.9447
10886031 FBJ osteosarcoma oncogene Fos NM_022197 0.008085 2.43039
10797527 growth arrest and DNA-damage-inducible, gamma Gadd45 g NM_001077640 0.01519 2.2081
10784120 gap junction protein, beta 6 Gjb6 NM_053388 0.033887 −2.2151
10849841 interleukin 1 beta Il1b NM_031512 0.046205 2.18761
10862908 interleukin 23 receptor Il23r XM_001067609 0.03848 2.92018
10733553 interferon regulatory factor 1 Irf1 NM_012591 0.005382 2.70651
10867306 hypothetical protein LOC683514 LOC683514 NM_001127569 0.028303 2.1278
10934056 moesin Msn NM_030863 0.031765 2.04966
10896814 myelocytomatosis oncogene Myc NM_012603 0.007411 2.7792
10920860 myeloid differentiation primary response gene 88 Myd88 NM_198130 0.014129 2.34728
10926588 nuclear factor of kappa light polypeptide gene enhancer i Nfkbie NM_199111 0.014731 2.17613
10750848 nuclear factor of kappa light polypeptide gene enhance Nfkbiz NM_001107095 0.00217 2.32035
10823365 purinergic receptor P2Y, G-protein coupled 12 P2ry12 NM_022800 0.017115 −2.38721
10792421 plasminogen activator, tissue Plat NM_013151 0.004342 2.38492
10911484 protogenin homolog (Gallus gallus) Prtg NM_001037651 0.027196 2.04521
10842475 protein tyrosine phosphatase, non-receptor type 1 Ptpn1 NM_012637 0.002949 2.18916
10821581 similar to hypothetical protein MGC42105 RGD1308116 ENSRNOT00000021964 0.013255 −2.2474
10710930 similar to hypothetical protein DKFZp434I2117 RGD1308215 NM_001106296 0.016796 −2.2475
10803006 similar to hypothetical protein B230399E16 RGD1559694 ENSRNOT00000020858 0.034301 −2.49615
10882514 RGD1560224 RGD1560224 ENSRNOT00000009292 0.048646 −2.31446
10855681 similar to hypothetical protein RGD1562590 ENSRNOT00000015469 0.006687 2.09732
10800434 ring finger protein 125 Rnf125 NM_001108424 0.037824 2.3249
10893918 strawberry notch homolog 2 (Drosophila) Sbno2 NM_001108068 0.007136 2.23202
10765195 selectin, platelet Selp NM_013114 0.03163 2.27171
10704505 solute carrier family 1 (neutral amino acid transporter), Slc1a5 NM_175758 0.028834 2.70661
10736795 schlafen 2 Slfn2 NM_001107031 0.048056 2.03465
10717935 superoxide dismutase 2, mitochondrial Sod2 NM_017051 0.039527 2.05701
10781273 stanniocalcin 1 Stc1 NM_031123 0.048406 2.26891
10869149 T-cell acute lymphocytic leukemia 2 Tal2 NM_001109462 0.012626 2.32825
10783880 transglutaminase 1, K polypeptide Tgm1 NM_031659 0.012214 2.7564
10887306 tumor necrosis factor, alpha-induced protein 2 Tnfaip2 NM_001137633 0.038454 2.32289
10858967 tumor necrosis factor receptor superfamily, member 1a Tnfrsf1a NM_013091 0.013832 2.36185
10829313 transient receptor potential cation channel, subfamily Trpm2 NM_001011559 0.009704 −2.04814
10802422 tubulin, beta 6 Tubb6 NM_001025675 0.015119 2.4974
10802995 zinc finger protein 516 Znf516 ENSRNOT00000021768 0.000278 2.01399
10813949 zinc finger protein 622 Znf622 ENSRNOT00000014423 0.011767 2.11
10821585 —   — 0.001925 −2.09732
10802710 —   — 0.005024 2.05529
10857403 —   — 0.007403 2.00653
10813885 —   — 0.00781 2.73034
10859195 —   — 0.025583 2.49356
10752799 —   — 0.026753 3.52422

Genes and ncRNAs (44 known genes, 6 ncRNAs) whose expression was significantly regulated by light damage (LD), and whose regulation was reduced below criterion when the retina was conditioned by photobiomodulation (PBM) and by saffron. These reductions in regulation may be important for the protective effects of PBM and saffron.

Natoli, Mol Vis 2010; 16:1801-1822. http://www.molvis.org/molvis/v16/a196

©2010 Molecular Vision http://www.molvis.org/molvis/

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