Figure 1. Pedigree and haplotypes of the posterior polar cataract family. Square and circles symbols denote males and females respectively; affected individuals are shaded black; the proband is identified by an arrow. Haplotyping markers are shown at the left of each generation. Black and white bars depict the disease and non-disease associated haplotype respectively. Haplotype analysis defined the causative gene as being between D17S921 and D17S800 on 17p12-21.2.