Figure 3. Resveratrol upregulated the expression of SOD-1, HO-1, and catalase. A: western blotting analysis of SOD-1, HO-1, and catalase at different time points (6, 12, 24, and 48 h) after pretreatment with 20.0 μM resveratrol. B: western blotting analysis of SOD-1, HO-1, and catalase 12 h after pretreatment with different concentration of resveratrol (2.5, 5.0, 10.0, and 20.0 μM). The expression levels of RES pretreated cells significantly increased compared with control cells (p<0.05), and the expression levels were proportional to the concentration of resveratrol.