Figure 4. Relationships between potential antioxidant and vascular endothelial growth factor and between Nε-hexanoyl-lysine and vascular endothelial growth factor in the vitreous body and serum from proliferative diabetic retinopathy and macular hole patients. A: The vitreous concentrations of PAO and VEGF displayed a significant correlation (r=0.39, p<0.05). B: In the serum, there was no significant correlation between PAO and VEGF concentrations. C: The HEL and VEGF concentrations in the vitreous showed a significant correlation (r=0.42, p<0.05). D: In the serum, there was no significant correlation between HEL and VEGF concentrations. Open circles and closed circles indicate MH and PDR patients, respectively (vitreous body). Open triangles and closed triangles indicate MH and PDR patients, respectively (serum). Correlations were examined using the Pearson's product-moment correlation coefficient.