Figure 4 of Hu, Mol Vis 2010; 16:1415-1428.


Figure 4. Morphological changes were observed in the Müller glia of protein O-mannose N-acetylglucosaminyltransferase 1 knockout retinas. Adult retinal sections were immunostained with antibodies against cellular retinaldehyde-binding protein (CRALBP; A and B), Kir4.1 (C and D), and aquaporin-4 (AQP-4; E and F). Fluorescence micrographs shown in A, C, and E are from wild type retinas and fluorescence micrographs shown in B, D, and F are from knockout retinas. Note the protrusion of Müller glia endfeet intro the vitreous (arrows in B) and reduced levels of Kir4.1 and AQP-4 at sites lacking the inner limiting membrane (asterisks in D and F). The scale bar in F is equal to 100 μm. Abbreviations: AQP-4 represents aquaporin-4; CRALBP represents cellular retinaldehyde-binding protein; DAPI represents 4',6-diamidino-2-phenylindole; INL represent inner nuclear layer; ILM represents inner limiting membrane; IPL represents inner plexiform layer; ONL represents outer nuclear layer; OPL represents outer plexiform layer.