Figure 3. Protein O-mannose N-acetylglucosaminyltransferase 1 knockout retinas exhibit ectopia of retinal ganglion cells. Transmission and scanning electron microscopy was performed for the adult retina. Transmission electromicroscopic micrographs (A, B) and scanning electron microscopic micrographs (C, D) are shown. (A, C) show the wild type retinas. (B, D) show the knockout retinas. Note the presence of ectopic retinal ganglion cells (dark circles) and inner plexiform layer components (dark square). Asterisks indicate the location of the inner limiting membrane. The scale bar in A is equal to 2 μm. The scale bar in B is equal to 10 μm. The scale bar in D is equal to 10 μm for C and D. +/+ represents wild type; −/− represents homozygous knockout.