Figure 2. Disruptions of the inner limiting membrane in protein O-mannose N-acetylglucosaminyltransferase 1 (POMGnT1) knockout retina. Transmission electron microscopy was carried for the adult retinas. Micrographs of transmission electron microscopy of wild type (A, C) and knockout (B, D) retinas are shown. Note that the wild-type inner limiting membrane was continuous (arrowheads in A). Knockout inner limiting membrane was discontinuous (arrows in B) with protrusion of Müller glial processes into the vitreous humor. The knockout Bruch’s membrane (arrowheads in D) was normal. The scale bar in B is equal to 500 nm for A and B. The scale bar in D is equal to 500 nm for C and D. +/+ represents wild type; −/− represents homozygous knockout.