Figure 5 of Lewis, Mol Vis 2010; 16:1361-1372.


Figure 5. Three images illustrating the indentation or “notch” within a single Muller cell nucleus. A, B: Laser scanning confocal images of rabbit retina detached for 3 days and labeled with both anti-bromodeoxyuridine (BrdU; red) and anti-vimentin (green). B is the same image as shown in A, with the two colors separated to better visualize the vimentin filaments (green) and the notch in the (single) nucleus (red, inset). C, D: Electron micrographs of normal rabbit (C) and 50-day detached cat (D) retinas showing a notch within Muller cell nuclei (arrows). Note the Müller cell nucleus in D now resides among the dark photoreceptor nuclei after detachment. Abbreviations: ONL represents outer nuclear layer; INL represents inner nuclear layer; GCL represents ganglion cell layer. Scale bars equal to 10 µm A, B; 5 µm C, D.