Table 3 of Shyam, Mol Vis 2010; 16:122-129.

Table 3. Categorization of Wnt components identified in human trabecular meshwork (TM) cells.

Component in Wnt pathway Wnt/β-catenin pathway Wnt/planar cell polarity pathway Wnt/Ca2+ pathway
Wnt ligand Wnt3, Wnt2b Wnt5a, Wnt5b Wnt5a, Wnt5b
Transduction protein Dsh2 Dsh1, Dsh2, Dsh3 Dsh3
Receptor Fzd1, Fzd5, Fzd7, LRP5, LRP6 Fzd2 Fzd4, Fzd2
β-Catenin and Degradation complex CTNNB1, GSK3β, APC NA NA
Transcription factor TCF3, TCF4, TCF7 NA NA
Inhibitor Dkk1, Dkk2, sFRP1, sFRP2, sFRP3 NA NA