Table 1 of Ju, Mol Vis 2010; 16:1331-1342.

Table 1. Effects of increased optic atrophy type 1 (OPA1) expression on the central, middle and peripheral retinal ganglion cell (RGC) survival from 9-month-old glaucomatous DBA/2J mice.


Strain
Age (mo)
Treatment		 RGC density per retina (RGCs/mm2)
Central Middle Peripheral
C57BL/6 9 AAV2-CMV-GFP 5208±522 4389±555 3000±570
DBA/2J 9 AAV2-CMV-GFP 3539±370* 2922±367* 1585±160*
DBA/2J 9 AAV2-WT mOPA1 4260±712** 3820±470** 2775±450**

Values are given as means±SD. Comparison of three experimental conditions was evaluated using one-way ANOVA (ANOVA) and the Bonferroni t-test. *Significant at p<0.05 compared with non-glaucomatous C57BL/6 mice transfected with adeno-associated virus serotype 2-cytomegalovirus-green fluorescent protein (AAV2-CMV-GFP), n=4 retinal flatmounts/mice/group. **Significant at p<0.05 compared with glaucomatous DBA/2J mice transfected with AAV2-CMV-GFP, n=7 retinal flatmounts/mice/group.

Ju, Mol Vis 2010; 16:1331-1342. http://www.molvis.org/molvis/v16/a147

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