Table 2 of Zerbib, Mol Vis 2010; 16:1324-1330.


Table 2. Genotype distributions of Y402H of CFH and rs10490924 of ARMS2 among the AMD patients and controls.

Genotypes Cases Controls Global p values Crude OR CI95%*, p Adjusted OR CI95%†, p
CFH Y402H (rs1061170)
TT 229 (21.2%) 160 (39.4%) <0.0001 1 (ref) 1 (ref)
TC 551 (51.1) 192 (47.3%)   2.0 [1.6–2.6]
p<0.0001 2.3 [1.7–3.2]
<0.0001
CC 299 (27.7%) 54 (13.3%)   3.9 [2.7–5.5]
p<0.0001 4.5 [2.9–7.0]
<0.0001
ARMS2 (rs10490924)
GG 339 (31.4%) 253 (63.7%) <0.0001 1 (ref) 1 (ref)
GT 507 (46.9%) 129 (32.5%)   2.9 [2.3–3.8]
<0.0001 3.0 [2.2–4.1]
<0.0001
TT 234 (21.7%) 15 (3.8%)   11.6 [6.7–20.1]
<0.0001 13.2 [7.2–24.2] <0.0001